Hydrochloric Acid → HCID 178516626, compound

HRID 41768Notes

Reaction equation

HRID 41768 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][C:18]([N:21]5[CH2:26][CH2:25][O:24][CH2:23][CH2:22]5)=[CH:17][CH:16]=4)[C:13](=[O:27])[CH:12](C(OCC)=O)[C:11]3=[O:33])=[CH:9][C:4]=2[N:3]=[CH:2]1.Cl>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][C:18]([N:21]5[CH2:22][CH2:23][O:24][CH2:25][CH2:26]5)=[CH:17][CH:16]=4)[C:13](=[O:27])[CH2:12][C:11]3=[O:33])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178470025HCID 178470025, compound

Product 1

HCID 178516626HCID 178516626, compound

Procedure

The compound was synthesized starting from ethyl 1-(1H-benzo[d]imidazol-5-yl)-5-(4-morpholinophenyl)-2,4-dioxo-pyrrolidine-3-carboxylate (which may be prepared in accordance with the procedure described for Intermediate 8; 0.12 g, 0.2676 mmol) and 5 N aqueous hydrochloric acid (6 ml) according to the method described in Method 1, step 3.

Workup

  1. customThe compound was synthesized
  2. custommay be prepared in accordance with the procedure

Sources & evidence

ORD record
ord-81c5129b7510477c802ec24209b6b9c2
Source dataset
uspto-grants-2013_09
Patent number
US08530670B2

Reaction notes

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