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HRID417874

反应详情

EQUATION

反应方程式

HRID 417874 的结构方程式

REACTANTS

反应物

4
结构：c1c[nH]cn1
HCID795

Imidazole

C3H4N2

结构：ClCCl
HCID6344

Dichloromethane

CH2Cl2

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：C#CCCCOS(C)(=O)=O
HCID12476209

Pent-4-yn-1-yl methanesulfonate

C6H10O3S

PRODUCTS

生成物

1
结构：C#CCCCn1ccnc1
HCID13865366

未命名化合物

收率 53.8%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O
溶剂HCID962

Water

H2O

结构：CCC(C)=O
溶剂HCID6569

Methyl ethyl ketone

C4H8O

PROCEDURE

实验过程

A mixture of pent-4-ynyl methanesulfonate (1.06 g), imidazole (534 mg) and K2CO3 (3.66 g) in 2-butanone (11 mL) was heated to reflux overnight. Work-up (DCM, H2O), drying (Na2SO4) and concentration gave 1-(pent-4-ynyl)-1H-imidazole (472 mg).

WORKUP

后处理

  1. temperaturewas heated
  2. temperatureto reflux overnight
  3. customdrying
  4. concentration(Na2SO4) and concentration