Sodium Hydroxide → HCID 57863014, compound

Participants

Reaction Steps

A similar procedure as described in Example 40, step 8 was used, starting from 4-[3-[6-(5,4′-bis-methanesulfonyl-biphenyl-3-yloxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (67 mg, 0.09 mmol) and 1.0 N aqueous sodium hydroxide (0.9 mL) to afford 4-[3-[6-(5,4′-bis-methanesulfonyl-biphenyl-3-yloxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy]-butyric acid (35 mg, 57%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C33H40O10S2 (M+Na)+ 683.1955, found 683.1954.

Provenance & Evidence