Sodium Hydroxide → HCID 57863050, compound

Participants

Reaction Steps

A similar procedure as described in Example 40, step 8 was used, starting from 4-[3-[6-(3-ethanesulfonyl-5-thiophen-3-yl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (111 mg, 0.17 mmol) and 1.0 N aqueous sodium hydroxide (1.7 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(3-ethanesulfonyl-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy]-butyric acid (53 mg, 52%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C31H38O8S2 (M+Na)+ 625.1900, found 625.1904.

Provenance & Evidence