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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 418346Generated: October 30, 2026

Hydrochloric Acid → HCID 86639092, compound

https://huagongshe.com/reaction/418346

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN-[4-[(Dimethylamino)methyl]-2-thiazolyl]acetamideHCID 57634222—
SolventEthanolHCID 702—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86639092HCID 86639092—

Reaction Conditions

Temperature50 °C

Reaction Steps

Dissolved N-(4-dimethylaminomethyl-thiazol-2-yl)-acetamide (274 mg, 1.38 mmol) in 5 mL of EtOH. Added 2 mL of 4 M HCl in dioxane and heated at 50° C. for 16 h. LC-MS analysis indicated complete acetyl removal. Concentrated to give 274 mg of 4-dimethylaminomethyl-thiazol-2-ylamine dihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093266B2
Source datasetuspto-grants-2012_01
ORD IDord-18d1573500e74f709e0268243ee45b48
Source noteuspto-grants-2012_01