Sodium Hydroxide → HCID 10384843, compound

Participants

Reaction Steps

The product of Example 40 step b) (0.50 g) was suspended in THF (10 ml) and to it added 1M sodium hydroxide (1.24 ml) for the mixture to be stirred overnight at room temperature to complete the reaction. The solution was evaporated to dryness and purified by Reverse Phase Preparative HPLC to give the title compound as a yellow solid (0.31 g).

Provenance & Evidence