Hydrochloric Acid → HCID 66651920, compound

HRID 418448Notes

Reaction equation

HRID 418448 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2.[C:12]([C:14]1[CH:15]=[CH:16][CH:17]=[C:18]2[C:23]=1[N:22]=[CH:21][CH:20]=[C:19]2Cl)#[N:13].Cl>O1CCOCC1>[C:12]([C:14]1[CH:15]=[CH:16][CH:17]=[C:18]2[C:23]=1[N:22]=[C:21]([C:10]1[C:9]3[C:4](=[CH:5][CH:6]=[C:7]([CH3:11])[CH:8]=3)[NH:3][C:2]=1[CH3:1])[CH:20]=[CH:19]2)#[N:13]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 709652,5-Dimethyl-1H-indoleHCID 147925994-Chloroquinoline-8-carbonitrile

Product 1

HCID 66651920HCID 66651920, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The sub-title compound was prepared by the method of Example 40 step a, using 2,5-dimethyl indole and 8-cyano-4-chloroquinoline and 1 molar equivalent of 4M HCl in dioxane.

Sources & evidence

ORD record
ord-e67439b591644170b4129855f049e080
Source dataset
uspto-grants-2012_01
Patent number
US08093278B2

Reaction notes

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