反应详情

The product from step b) was heated to reflux in phosphorus oxychloride (80 ml) for 1 hour. The reagent was evaporated under reduced pressure to give an oil which was carefully poured into a mixture of ice/880 ammonia solution (400 ml) and stirred for 30 minutes. The solid was filtered off and dried in vacuo to give the sub-title compound (6.80 g).

1. customThe reagent was evaporated under reduced pressure
2. customto give an oil which
3. filtrationThe solid was filtered off
4. customdried in vacuo