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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 418654Generated: October 30, 2026

P-Anisidine → 3-(4-Methoxyanilino)-3-oxopropanoic acid

https://huagongshe.com/reaction/418654

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
ReactantN-(2-Methoxy-phenyl)-malonamic acidHCID 12664594—
Product3-(4-Methoxyanilino)-3-oxopropanoic acidHCID 1165853956%

Reaction Steps

Starting from 4-methoxyaniline and following the procedure described above for the synthesis of compound 27 (example 8, scheme 8), title compound 157 was obtained in 56% yield. MS (m/z): 210.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093264B2
Source datasetuspto-grants-2012_01
ORD IDord-f12416f22093495b8f4499dc47dbfc6d
Source noteuspto-grants-2012_01