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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 418676Generated: October 30, 2026

7-(2-fluoro-4-nitrophenoxy)-N',N'-dimethylthieno[3,2-b]pyridine-2-carbohydrazide → 7-(2-fluoro-4-nitrophenoxy)-N,N',N'-trimethylthieno[3,2-b]pyridine-2-carbohydrazide

https://huagongshe.com/reaction/418676

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-(2-fluoro-4-nitrophenoxy)-N',N'-dimethylthieno[3,2-b]pyridine-2-carbohydrazideHCID 58790007—
Reactant7-chloro-N,N',N'-trimethylthieno[3,2-b]pyridine-2-carbohydrazideHCID 58790308—
Product7-(2-fluoro-4-nitrophenoxy)-N,N',N'-trimethylthieno[3,2-b]pyridine-2-carbohydrazideHCID 5879038466%

Reaction Steps

Following the procedure described above for compound 238 (step 2, example 95, scheme 63) but replacing chloride 237 with compound 242, title compound 243 was obtained in 66% yield. MS (m/z): (M+1) 391.1 (100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093264B2
Source datasetuspto-grants-2012_01
ORD IDord-7ab1299fb4964515a956556c89650570
Source noteuspto-grants-2012_01