6-Oxabicyclo[3.1.0]hexane → HCID 66652106, compound

HRID 418903Notes

Reaction equation

HRID 418903 reaction equation
[CH:1]12[O:6][CH:2]1[CH2:3][CH2:4][CH2:5]2.Br[C:8]1[CH:13]=[C:12]([O:14][CH3:15])[CH:11]=[C:10]([O:16][CH3:17])[CH:9]=1>>[CH3:15][O:14][C:12]1[CH:13]=[C:8]([C@@H:2]2[CH2:3][CH2:4][CH2:5][C@H:1]2[OH:6])[CH:9]=[C:10]([O:16][CH3:17])[CH:11]=1

Participants

3

Reactant 2

HCID 92446-Oxabicyclo[3.1.0]hexaneHCID 6391871-Bromo-3,5-dimethoxybenzene

Product 1

HCID 66652106HCID 66652106, compound

Procedure

Preparation 19 is prepared from cyclopentene oxide and 1-bromo-3,5-dimethoxybenzene in a manner similar to preparation 10. 1H NMR (CDCl3): 6.41 (s, 2H), 6.33(s, 1H), 4.15 (dd, J=7.5 Hz, 1H), 3.78 (s, 6H), 2.81 (dd, J=9.2 Hz, 1H), 2.1 (m, 2H), 1.9-1.5 (m, 6H).

Workup

  1. customPreparation 19

Sources & evidence

ORD record
ord-cdc00ef00f9f45b39ffd910c7f78824d
Source dataset
uspto-grants-2012_01
Patent number
US08093302B2

Reaction notes

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