反应详情

To a 200-mL, 2-necked flask was added 31.5 g (250 mmol) of 1,3,5-trihydroxybenzene. After replaced with argon, 25 mL of 28% ammonia and water were added thereto, and the resulting mixture was stirred in a water bath for 18 hours. Water was removed away in vacuo and 50 mL of isopropanol was added. The obtained mixture was ice-cooled for 2 hours to precipitate a solid and the precipitated solid was obtained by filtration. The solid was washed with isopropanol and then vacuum-dried, whereby a desired product was obtained (Quantity: 11.4 g, 91.3 mmol, Yield: 37%).

1. additionwere added
2. customWater was removed away in vacuo and 50 mL of isopropanol
3. additionwas added
4. temperaturecooled for 2 hours
5. customto precipitate a solid
6. customthe precipitated solid was obtained by filtration
7. washThe solid was washed with isopropanol
8. customvacuum-dried