3'-Isopropoxy-4'-methoxypropiophenone → 3'-Hydroxy-4'-methoxypropiophenone

HRID 41924Notes

Reaction equation

HRID 41924 reaction equation
C([O:4][C:5]1[CH:6]=[C:7]([C:13](=[O:16])[CH2:14][CH3:15])[CH:8]=[CH:9][C:10]=1[O:11][CH3:12])(C)C>C(OCC)(=O)C.CCCCCC>[OH:4][C:5]1[CH:6]=[C:7]([C:13](=[O:16])[CH2:14][CH3:15])[CH:8]=[CH:9][C:10]=1[O:11][CH3:12]

Participants

3

Reactant 1

HCID 667609483'-Isopropoxy-4'-methoxypropiophenone

Product 1

HCID 9197553'-Hydroxy-4'-methoxypropiophenone

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Concentration of fraction B (Rf 0.6 in 1:1 v/v ethyl acetate/hexane) afforded the starting ether 10 (207 mg, 50% recovery) as a white solid that was identical, as judged by 1H NMR spectroscopic analysis, with authentic material.

Sources & evidence

ORD record
ord-1fcc45850ae64be1a8e1913d412d0ca8
Source dataset
uspto-grants-2013_09
Patent number
US08536157B2

Reaction notes

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