HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Diaminoquinoline → HCID 178419901, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Diaminoquinoline | HCID 1514289 | — |
| Reactant | [1,5]Naphthyridine-3,4-diamine | HCID 22172703 | — |
| Product | HCID 178419901 | HCID 178419901 | — |
| Product | 1h-Imidazo[4,5-c][1,5]naphthyridine | HCID 178420735 | — |
Reaction Steps
In step (8) of Reaction Scheme I, a quinoline-3,4-diamine or [1,5]naphthyridine-3,4-diamine of Formula XXII is reacted with a carboxylic acid equivalent, which is selected such that it will provide the desired —CH2—(CH2)d-Hal substituent in a 1H-imidazo[4,5-c]quinoline or 1H-imidazo[4,5-c][1,5]naphthyridine of Formula XXIII. Suitable carboxylic acid equivalents include ortho esters, acid halides, and imidates or salts thereof.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093390B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-b02efb50cff94d86ad85c51031e4042c |
| Source note | uspto-grants-2012_01 |