HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 419293Generated: October 28, 2026
Hydrogen Bromide → 6-amino-10,11-dihydro-8H-[1,4]oxazino [4',3':1,2]imidazo[4,5-c]quinolin-3-ol
https://huagongshe.com/reaction/419293
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-(benzyloxy)-10,11-dihydro-8H-[1,4]oxazino[4',3':1,2]imidazo[4,5-c]quinolin-6-amine | HCID 11609909 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 6-amino-10,11-dihydro-8H-[1,4]oxazino [4',3':1,2]imidazo[4,5-c]quinolin-3-ol | HCID 135520079 | — |
Reaction Steps
A glass vial was charged with 3-(benzyloxy)-10,11-dihydro-8H-[1,4]oxazino[4′,3′:1,2]imidazo[4,5-c]quinolin-6-amine (0.1 g, 0.29 mmol) and a solution of 48% hydrogen bromide in acetic acid (4.0 mL). The mixture was heated at 100° C. overnight, cooled, and concentrated to provide 6-amino-10,11-dihydro-8H-[1,4]oxazino [4′,3′:1,2]imidazo[4,5-c]quinolin-3-ol as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08093390B2 |
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| Source dataset | uspto-grants-2012_01 |
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| ORD ID | ord-94c0cfbf5450405897ac710a1b46ecfe |
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| Source note | uspto-grants-2012_01 |
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