反应详情

温度

100 °C

A glass vial was charged with 3-(benzyloxy)-10,11-dihydro-8H-[1,4]oxazino[4′,3′:1,2]imidazo[4,5-c]quinolin-6-amine (0.1 g, 0.29 mmol) and a solution of 48% hydrogen bromide in acetic acid (4.0 mL). The mixture was heated at 100° C. overnight, cooled, and concentrated to provide 6-amino-10,11-dihydro-8H-[1,4]oxazino [4′,3′:1,2]imidazo[4,5-c]quinolin-3-ol as an off-white solid.

1. temperaturecooled
2. concentrationconcentrated