HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178478538, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 178451791 | HCID 178451791 | — |
| Product | HCID 178478538 | HCID 178478538 | — |
Reaction Steps
Dissolve 4-[4-(3-Chloro-phenyl)-1H-imidazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester (171 mg; 472.54 μmoles) in dichloromethane (3 mL; 46.80 mmoles) and slowly add hydrogen chloride (4 mL; 16.00 mmoles) (4M HCl in dioxane) at room temperature. Stir the solution 1 h. Concentrate in vacuo (2×DCM) to give 4-[4-(3-Chloro-phenyl)-1H-imidazol-2-yl]-piperidine hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093383B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-feba5cefb4ac420d9937a737e2c89f74 |
| Source note | uspto-grants-2012_01 |