HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → methyl 1H-tetrazol-1-ylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 1-Tetrazolylacetic acid | HCID 543207 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | methyl 1H-tetrazol-1-ylacetate | HCID 3153776 | — |
Reaction Steps
A mixture of tetrazol-1-yl acetic acid (5 g, 39 mmol) and 4M hydrochloric acid in dioxan (100 μL) in methanol (50 mL) was heated under reflux for 18 hours. The cooled mixture was evaporated under reduced pressure to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093400B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-1f14cc65617e4ae1985a9137fda2cfc7 |
| Source note | uspto-grants-2012_01 |