HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorophenylboronic acid → 5-Bromo-2-(2-chlorophenyl)pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorophenylboronic acid | HCID 2734322 | — |
| Reactant | 5-Bromo-2-iodopyrimidine | HCID 7006651 | — |
| Product | 5-Bromo-2-(2-chlorophenyl)pyrimidine | HCID 49758702 | 69% |
Reaction Steps
Obtained (0.400 g, yield 69%) following the procedure described in Intermediate 21, starting with 5-bromo-2-iodopyrimidine (2.14 mmol, 0.61 g), 2-chlorophenylboronic acid (2.37 mmol, 0.37 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536165B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-190b9fcfb21842519188326b069865c5 |
| Source note | uspto-grants-2013_09 |