HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57586564, compound → HCID 25191878, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57586564 | HCID 57586564 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 25191878 | HCID 25191878 | 56% |
Reaction Steps
A similar procedure as described in Example 1, step 3 was used, starting from 4-[3-{6-[3,5-bis-(2-fluoro-pyridin-4-yl)-phenoxy]-hexyl}-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (220 mg, 0.32 mmol) and 1.0 N aqueous NaOH (10 mL) to afford 4-[3-{6-[3,5-bis-(2-fluoro-pyridin-4-yl)-phenoxy]-hexyl}-2-(2-carboxy-ethyl)-phenoxy]-butyric acid (110 mg, 56%) as an amorphous white solid: ES(+)-HRMS m/e calculated for C35H36F2N2O6 (M+H)+ 619.2614, found 619.2615.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093385B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-d388c8900dde479aa2b8f81c86d812b3 |
| Source note | uspto-grants-2012_01 |