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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420352Generated: October 29, 2026

HCID 57586564, compound → HCID 25191878, compound

https://huagongshe.com/reaction/420352

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57586564HCID 57586564—
SolventSodium HydroxideHCID 14798—
ProductHCID 25191878HCID 2519187856%

Reaction Steps

A similar procedure as described in Example 1, step 3 was used, starting from 4-[3-{6-[3,5-bis-(2-fluoro-pyridin-4-yl)-phenoxy]-hexyl}-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (220 mg, 0.32 mmol) and 1.0 N aqueous NaOH (10 mL) to afford 4-[3-{6-[3,5-bis-(2-fluoro-pyridin-4-yl)-phenoxy]-hexyl}-2-(2-carboxy-ethyl)-phenoxy]-butyric acid (110 mg, 56%) as an amorphous white solid: ES(+)-HRMS m/e calculated for C35H36F2N2O6 (M+H)+ 619.2614, found 619.2615.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093385B2
Source datasetuspto-grants-2012_01
ORD IDord-d388c8900dde479aa2b8f81c86d812b3
Source noteuspto-grants-2012_01