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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420377Generated: November 2, 2026

Potassium Iodide → HCID 57586542, compound

https://huagongshe.com/reaction/420377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium IodideHCID 4875—
ReactantSodium NitriteHCID 23668193—
ReactantHCID 57586478HCID 57586478—
ProductHCID 57586542HCID 5758654278%

Reaction Steps

A similar procedure as described in Example 12, step 5 was used, starting from 3′-fluoro-5-methoxy-biphenyl-3-ylamine (940 mg, 4.32 mmol), sodium nitrite (545 mg, 7.79 mmol), and potassium iodide (1.44 mg, 8.65 mmol) to afford 3′-fluoro-3-iodo-5-methoxy-biphenyl (1.1 g, 78%) as an amorphous light yellow oil: ES(+)-HRMS m/e calculated for C13H10FIO (M+H)+ 329.1190, found 329.1192.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093385B2
Source datasetuspto-grants-2012_01
ORD IDord-4047dbda1ba4442aa969b21db34e97ff
Source noteuspto-grants-2012_01