Sodium Hydroxide → HCID 57586519, compound

Participants

Reaction Steps

A similar procedure as described in Example 12, step 9 was used, starting from 4-{2-(2-ethoxycarbonyl-ethyl)-3-[6-(3′-fluoro-5-iodo-biphenyl-3-yloxy)-hexyl]-phenoxy}-butyric acid ethyl ester (2.23 g, 3.17 mmol) and aqueous 1.0 N sodium hydroxide (31.65 mL) to obtain 4-{2-(2-carboxy-ethyl)-3-[6-(3′-fluoro-5-iodo-biphenyl-3-yloxy)-hexyl]-phenoxy}-butyric acid (1.86 g, 91%) as a light yellow oil: ES(+)-HRMS m/e calculated for C31H34FIO6 (M+Na)+ 671.1276, found 671.1271.

Provenance & Evidence