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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420448Generated: October 30, 2026

Sodium Cyanide → HCID 54741066, compound

https://huagongshe.com/reaction/420448

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CyanideHCID 8929—
ReactantHCID 66658633HCID 66658633—
ReactantHCID 66658653HCID 66658653—
ProductHCID 54741066HCID 54741066—

Reaction Steps

tert-Butyl 2-(2-cyano-5-hydroxy-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamido)acetate. The title compound is prepared by reaction of tert-butyl 2-(5-hydroxy-8-methyl-2-(methylsulfonyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamido)acetate with sodium cyanide according to the procedure described in Bioorg. Med. Chem. Lett., 17, 6206 (2007).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08097620B2
Source datasetuspto-grants-2012_01
ORD IDord-0fda0e15ffdd461f8a26c7d44b6ec357
Source noteuspto-grants-2012_01