HRID420458

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23094070

2-(4-Bromophenyl)-1-phenyl-1H-benzimidazole

C19H13BrN2

HCID23094085

未命名化合物

PRODUCTS

生成物

结构：c1ccc(-n2c(-c3cncc(-c4c5ccccc5c(-c5ccc6ccccc6c5)c5ccccc45)c3)nc3ccccc32)cc1

HCID86643772

未命名化合物

PROCEDURE

实验过程

Almost the same procedure as step (2) in Synthesis Example 1 was carried out except that corresponding 2-(5-bromopyridine-3-yl)-1-phenyl-1H-benzimidazole was used instead of 2-(4-bromophenyl-phenyl-1H-benzimidazole, resultantly obtaining an aimed compound (Compound (4-6) (yield: 36%). As a result of MS analysis, it was recognized that m/e=573 for aimed substance's molecular weight of 573.22.

WORKUP

后处理

customAlmost the same procedure as step (2) in Synthesis Example 1

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8b75b90c79ba4e308c354d7609e2b5dc
来源数据集: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08097349B2
来源说明: uspto-grants-2012_01

反应 SMILES

Br[C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:11]3[CH:19]=[CH:20][CH:21]=[CH:22][C:10]=3[N:9]=2)[CH:5]=[N:6][CH:7]=1.Br[C:24]1[CH:29]=[CH:28][C:27]([C:30]2N(C3C=CC=CC=3)C3C=CC=CC=3N=2)=[CH:26][CH:25]=1>>[CH:29]1[C:28]2[C:27](=[CH:30][CH:11]=[CH:10][CH:22]=2)[CH:26]=[CH:25][C:24]=1[C:26]1[C:25]2[C:24](=[CH:7][CH:2]=[CH:3][CH:4]=2)[C:29]([C:2]2[CH:3]=[C:4]([C:8]3[N:12]([C:13]4[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=4)[C:11]4[CH:19]=[CH:20][CH:21]=[CH:22][C:10]=4[N:9]=3)[CH:5]=[N:6][CH:7]=2)=[C:28]2[C:27]=1[CH:30]=[CH:14][CH:13]=[CH:18]2