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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42052Generated: October 25, 2026

2-(Trifluoromethyl)benzeneboronic acid → 5-Bromo-2-(2-(trifluoromethyl)phenyl)pyrimidine

https://huagongshe.com/reaction/42052

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzeneboronic acidHCID 2734387—
Reactant5-Bromo-2-iodopyrimidineHCID 7006651—
Product5-Bromo-2-(2-(trifluoromethyl)phenyl)pyrimidineHCID 4975869752%

Reaction Steps

Obtained (52% yield) following the procedure described in Intermediate 21, starting with 5-bromo-2-iodopyrimidine and 2-(trifluoromethyl)phenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536165B2
Source datasetuspto-grants-2013_09
ORD IDord-3b57758fd6614679a9a60fa13dd81082
Source noteuspto-grants-2013_09