Phenylboronic Acid → HCID 67393786, compound

HRID 42065Notes

Reaction equation

Br[C:2]1[N:7]=[CH:6][C:5]([NH:8][C:9]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][C:10]=2[C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])=[CH:4][C:3]=1[Cl:23].[C:24]1(B(O)O)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[Cl:23][C:3]1[CH:4]=[C:5]([NH:8][C:9]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][C:10]=2[C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[C:6]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[N:7][CH:2]=1

Participants

Reactant 2

HCID 66827Phenylboronic Acid

HCID 86657264HCID 86657264, compound

Product 1

HCID 67393786HCID 67393786, compound

Procedure

Obtained (0.008 g, 3% of yield) following the procedure described in Example 8 (step A) starting with Intermediate 20B (0.58 mmol, 0.230 g) and phenylboronic acid (0.87 mmol, 0.106 g).

Workup

customObtained
custom(0.008 g, 3% of yield)

Sources & evidence

ORD record: ord-70815eccb0224bf8b688b8d017848865
Source dataset: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08536165B2

Reaction notes

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