HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Dimethylbutanoyl chloride → 8-(3,3-Dimethylbutanoyl)-2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Dimethylbutanoyl chloride | HCID 81514 | — |
| Reactant | 2-(4-(2,2,2-Trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione | HCID 58478415 | — |
| Product | 8-(3,3-Dimethylbutanoyl)-2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione | HCID 53482687 | — |
Reaction Steps
This material was prepared as a white solid in analogy to example 3) from 2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione, product of example 10 step A), and 3,3-dimethyl-butyryl chloride. MS (ESI): 425.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097634B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-22dff49742fb4fdd8d744606acc682ff |
| Source note | uspto-grants-2012_01 |