Epichlorohydrin → 1-[(Oxiran-2-yl)methyl]pyrrolidine

HRID 420844Notes

Reaction equation

[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:6]([CH:8]1[O:10][CH2:9]1)Cl>>[O:10]1[CH2:9][CH:8]1[CH2:6][N:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 7835Epichlorohydrin

HCID 31268Pyrrolidine

Product 1

HCID 133136171-[(Oxiran-2-yl)methyl]pyrrolidine

Procedure

By using pyrrolidine (3 ml) and (±)-epichlorohydrin (2.9 ml) as starting materials, the title compound (2.10 g) was obtained in the same manner as that of Reference Example 33.

Sources & evidence

ORD record: ord-bd6b1def4b3b4403b668bd9e1229f35d
Source dataset: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08097708B2

Reaction notes

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