反应详情

Lithium aluminum hydride (271 mg) was suspended in tetrahydrofuran, the suspension was added with 4-nitro-DL-phenylalanine (1.0 g) under ice cooling, and the mixture was stirred for 1 hour. The reaction mixture was added successively with distilled water, 15% aqueous sodium hydroxide and distilled water, and the mixture was stirred for 12 hours. The reaction mixture was filtered, and the resulting filtrate was concentrated under reduced pressure to obtain the title compound (516 mg).

1. distillationdistilled water
2. stirringthe mixture was stirred for 12 hours
3. filtrationThe reaction mixture was filtered
4. concentrationthe resulting filtrate was concentrated under reduced pressure