HRID420935

反应详情

EQUATION

反应方程式

HRID 420935 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

The title compound was prepared by heating 2-carboxymethyl-1-(4-isopropoxyphenyl)-5-(5-trifluoromethyl-2-pyridinyloxy)indole-3-carboxylic acid ethyl ester (140 mg, 0.26 mmol, see step (b) Example 25), NaOH (aq. 2 M, 0.6 mL) and EtOH (1 mL) at 90° C. for 7 h. Yield 124 mg (92%), nip 202° C.

WORKUP

后处理

  1. customYield 124 mg (92%), nip 202° C.