HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butylphenylboronic acid → 5-(4-tert-Butylphenyl)-3-formyl-1-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butylphenylboronic acid | HCID 2734320 | — |
| Reactant | 5-Bromo-3-formyl-1-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester | HCID 57419920 | — |
| Product | 5-(4-tert-Butylphenyl)-3-formyl-1-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester | HCID 86628822 | — |
Reaction Steps
The sub-title compound was prepared in accordance with step (a) Example 67 from 5-bromo-3-formyl-1-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester (4.07 g, 9.46 mmol; see step (b) above) and 4-tert-butylphenylboronic acid (2.53 g, 14.19 mmol). Yield 4.16 g (91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097623B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-f51e99e1953a43ce88e5d10dc7d5ff6f |
| Source note | uspto-grants-2012_01 |