Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 421071Generated: October 26, 2026

Benzenamine, 3,5-bis(trifluoromethyl)- → N-[3,5-Bis(trifluoromethyl)phenyl]-4-hydroxyisophthalamic acid methyl ester

https://huagongshe.com/reaction/421071

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant2-Hydroxy-5-(methoxycarbonyl)benzoic acidHCID 12717060—
ProductN-[3,5-Bis(trifluoromethyl)phenyl]-4-hydroxyisophthalamic acid methyl esterHCID 1132724991.5%

Reaction Steps

Using 4-hydroxyisophthalic acid 1-methyl ester and 3,5-bis(trifluoromethyl)-aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08097759B2
Source datasetuspto-grants-2012_01
ORD IDord-11e748437fb349c6855443dcb214865b
Source noteuspto-grants-2012_01