HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzylpiperidine → 2-Benzyl-5-(4-benzylpiperidine-1-carbonyl)-N-[3,5-bis(trifluoromethyl)-phenyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzylpiperidine | HCID 31738 | — |
| Reactant | 4-benzyl-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acid | HCID 86595538 | — |
| Product | 2-Benzyl-5-(4-benzylpiperidine-1-carbonyl)-N-[3,5-bis(trifluoromethyl)-phenyl]benzamide | HCID 17860186 | 76.7% |
Reaction Steps
Using 4-benzyl-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acid and 4-benzylpiperidine as the raw materials, the same operation as the example 84(3) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097759B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-1b1d6bfbb0374764b0e934e9bfdb2da8 |
| Source note | uspto-grants-2012_01 |