3,5-Dichloroaniline → N-(3,5-Dichlorophenyl)-5-fluoro-2-hydroxybenzamide

HRID 421127Notes

Reaction equation

HRID 421127 reaction equation
[F:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([Cl:20])[CH:19]=1)[NH2:16]>>[Cl:12][C:13]1[CH:14]=[C:15]([NH:16][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([F:1])[CH:3]=[CH:4][C:5]=2[OH:11])[CH:17]=[C:18]([Cl:20])[CH:19]=1

Participants

3

Reactant 2

HCID 122813,5-DichloroanilineHCID 676585-Fluorosalicylic acid

Product 1

HCID 17860238N-(3,5-Dichlorophenyl)-5-fluoro-2-hydroxybenzamideYield 33.3%

Procedure

Using 5-fluorosalicylic acid and 3,5-dichloroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-59f080ad836444588cf0b414d724baf0
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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