5-Bromosalicylic acid → 5-Bromo-N-(2,5-dimethoxyphenyl)-2-hydroxybenzamide

HRID 421146Notes

Reaction equation

HRID 421146 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][C:15]=1[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:17]=[C:18]([O:21][CH3:22])[CH:19]=[CH:20][C:14]=1[O:13][CH3:12])=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 76132,5-Dimethoxyaniline

Product 1

HCID 178602145-Bromo-N-(2,5-dimethoxyphenyl)-2-hydroxybenzamideYield 39.7%

Procedure

Using 5-bromosalicylic acid and 2,5-dimethoxyaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-d97996f7a20d4c1ebaa0130ddc82e435
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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