5-Bromosalicylic acid → HCID 17860315, compound

HRID 421160Notes

Reaction equation

HRID 421160 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[S:14][C:15]([CH3:18])=[CH:16][N:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[S:14][C:15]([CH3:18])=[CH:16][N:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 3517702-Amino-5-methylthiazole

Product 1

HCID 17860315HCID 17860315, compoundYield 12.9%

Procedure

Using 5-bromosalicylic acid and 2-amino-5-methylthiazole as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-c75c97d7efbe440f816552a9959346f2
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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