HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Boc-Azetidine-3-carboxylic acid → 3beta-(N-(tert-Butoxycarbonyl)azetidin-3-ylcarbonyloxy)androstane-6,17-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Boc-Azetidine-3-carboxylic acid | HCID 2755981 | — |
| Edukt | 3beta-Hydroxy-5alpha-androstan-6,17-dione | HCID 69012642 | — |
| Produkt | 3beta-(N-(tert-Butoxycarbonyl)azetidin-3-ylcarbonyloxy)androstane-6,17-dione | HCID 69009436 | 65% |
Reaktionsschritte
Prepared in 65% yield from 3β-hydroxyandrostane-6,17-dione and 1-(tert-butoxycarbonyl)-3-azetidinecarboxylic acid by the procedure described in Prepn. 43. 1H-NMR (300 MHz, DMSO-d6, ppm from TMS): δ 4.66 (1H, m), 4.50-1.00 (29H, m), 1.35 (9H, s), 0.78 (3H, s), 0.69 (3H, s).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08536160B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-e24ff23a939d43e0b0c3f559f688a598 |
| Quellennotiz | uspto-grants-2013_09 |