Mandelic Acid → HCID 66673326, compound

HRID 421538Notes

Reaction equation

HRID 421538 reaction equation
[OH-].[Na+].[C:3]([OH:13])(=[O:12])[CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[OH:5].[Cl-].[Zn+2:15].[Cl-]>O>[C:3]([O-:13])(=[O:12])[CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[OH:5].[Zn+2:15].[C:3]([O-:13])(=[O:12])[CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[OH:5]

Participants

5

Reactant 3

HCID 1292Mandelic AcidHCID 14798Sodium HydroxideHCID 3007855Zincchloride

Product 1

HCID 66673326HCID 66673326, compoundYield 61%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Conditions

Temperature
70 °C

Procedure

A solution of 47% (w/w) sodium hydroxide (5.5 g) is added to slurry of mandelic acid (7.6 g, 0.05 mol) in water (100 mL) at 70° C. to give a clear slightly alkaline solution. A solution of zinc chloride (3.4 g, 0.025 mol) in water (50 mL) is added and a precipitate is formed immediately. The mixture is stirred at 70° C. for further 2.5 hours. The precipitate is then filtered and dried to yield 5.6 g (61%) zinc mandelate as a fine white powder. IR absorption bands: 1592, 1404 and 1361 cm−1.

Workup

  1. customto give a clear slightly alkaline solution
  2. customa precipitate is formed immediately
  3. filtrationThe precipitate is then filtered
  4. customdried

Sources & evidence

ORD record
ord-b9a3f5dd5253452dba3cc75ffa134fb8
Source dataset
uspto-grants-2012_01
Patent number
US08101544B2

Reaction notes

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