Hydrochloric Acid → HCID 86611351, compound

HRID 421597Notes

Reaction equation

HRID 421597 reaction equation
C(OC([NH:8][C@@H:9]([CH3:16])/[CH:10]=[CH:11]/[C:12]([O:14][CH3:15])=[O:13])=O)(C)(C)C.[ClH:17]>O1CCOCC1>[ClH:17].[NH2:8][C@@H:9]([CH3:16])/[CH:10]=[CH:11]/[C:12]([O:14][CH3:15])=[O:13]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 10857231HCID 10857231, compound

Product 1

HCID 86611351HCID 86611351, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A solution of methyl (2E)(4S)-4-[(tert-butoxy)carbonylamino]pent-2-enoate (3.083 g, 13.45 mmol) in 4N hydrogen chloride in dioxane was stirred at room temperature for 1 hour. The volatiles were evaporated to give the title compound (2.2 g, 98%): ES-MS (m/z) 130.3 [M+1]+.

Workup

  1. customThe volatiles were evaporated

Sources & evidence

ORD record
ord-9c4e8aaa632a4abcb886ca8aee28fd85
Source dataset
uspto-grants-2012_01
Patent number
US08101588B2

Reaction notes

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