HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Propyl-2-bromopyrimidine → HCID 44820483, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Propyl-2-bromopyrimidine | HCID 10420346 | — |
| Reactant | Tert-butyl 4-[2-(4-cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate | HCID 44820148 | — |
| Product | HCID 44820483 | HCID 44820483 | — |
Reaction Steps
The title compound was prepared from tert-butyl 4-[2-(4-cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate (Example 13) (50 mg, 0.12 mmol) and 5-propyl-2-bromopyrimidine (33 μL, 0.24 mmol) following a procedure analogous to that in Example 48 as a white crystal (35 mg, yield 67%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536176B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-ab397bc407994d3999fbf2d28c09ebf1 |
| Source note | uspto-grants-2013_09 |