HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-[2-(4-cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate → HCID 67223777, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-[2-(4-cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate | HCID 44820148 | — |
| Reactant | 5-Pentyl-2-bromopyrimidine | HCID 86654266 | — |
| Product | HCID 67223777 | HCID 67223777 | — |
Reaction Steps
The title compound was prepared from tert-butyl 4-[2-(4-cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate (Example 13) (33 mg, 0.08 mmol) and 5-pentyl-2-bromopyrimidine (27 μL, 0.16 mmol) following a procedure analogous to that in Example 48 as a white crystal (24 mg, yield 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536176B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-6e0a66a316574685985f5e43e91c68ad |
| Source note | uspto-grants-2013_09 |