HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67083200, compound → 5-Pentyl-2-[4-[2-[4-(tetrazol-1-yl)phenoxymethyl]pyridin-5-yl]piperidin-1-yl]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67083200 | HCID 67083200 | — |
| Reactant | 5-Pentyl-2-bromopyrimidine | HCID 86654266 | — |
| Product | 5-Pentyl-2-[4-[2-[4-(tetrazol-1-yl)phenoxymethyl]pyridin-5-yl]piperidin-1-yl]pyrimidine | HCID 67083348 | — |
Reaction Steps
The title compound was prepared from tert-butyl 4-[2-[4-(tetrazol-1-yl)phenoxymethyl]pyridin-5-yl]piperidine-1-carboxylate (Example 17) (52 mg, 0.12 mmol) and 5-pentyl-2-bromopyrimidine (41 μL, 0.24 mmol) following a procedure analogous to that in Example 48 as a white crystal (26 mg, yield 45%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536176B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-e272d0b746cf4d2b8ffca9ca85ebe692 |
| Source note | uspto-grants-2013_09 |