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HRID421680

反应详情

EQUATION

反应方程式

HRID 421680 的结构方程式

REACTANTS

反应物

2
反应SMILES：O=C(O)c1ccc(-n2ccnc2)cc1
HCID736529

4-(1H-Imidazol-1-yl)benzoic acid

C10H8N2O2

反应SMILES：Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(N)c1
HCID16730560

未命名化合物

PRODUCTS

产物

1
反应SMILES：Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(NC(=O)c2ccc(-n3ccnc3)cc2)c1
HCID16730789

未命名化合物

PROCEDURE

实验过程

N-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide (0.15 mmol) was used in general procedure 2 with 4-(1H-imidazol-1-yl)benzoic acid (0.167 mmol). The product was purified by RP-HPLC to give N-(3-(4-(1-H-imidazol-yl)benzamido)-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide. MS (Q1) 500.0 (M)+

WORKUP

后处理

  1. customThe product was purified by RP-HPLC