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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 421693Generated: November 1, 2026

N-(5-amino-2-chlorophenyl)benzamide → N-(3-benzamido-4-chlorophenyl)-6-(bromomethyl)nicotinamide

https://huagongshe.com/reaction/421693

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(5-amino-2-chlorophenyl)benzamideHCID 721122—
Reactant6-(Bromomethyl)-3-pyridinecarboxylic acidHCID 21840978—
ProductN-(3-benzamido-4-chlorophenyl)-6-(bromomethyl)nicotinamideHCID 16730952—

Reaction Steps

N-(5-amino-2-chlorophenyl)benzamide (1.0 mmol) was used in general procedure 2 with 6-(bromomethyl)nicotinic acid (21.1 mmol) to give N-(3-benzamido-4-chlorophenyl)-6-(bromomethyl)-nicotinamide. MS (Q1) 444.0 (M)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08101610B2
Source datasetuspto-grants-2012_01
ORD IDord-c7b02a9d77324492aee2182a07c40ef0
Source noteuspto-grants-2012_01