HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 16731193, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | HCID 16731033 | HCID 16731033 | — |
| Product | HCID 16731193 | HCID 16731193 | — |
Reaction Steps
6-chloro-N-(4-chloro-3-(4-fluorobenzamido)phenyl)nicotinamide (0.17 mmol) was used in general procedure 3 with Boc-piperazine (0.868 mmol). The product was deprotected by treatment with TFA and purified by RP-HPLC to give N-(4-chloro-3-(4-fluorobenzamido)phenyl)-6-(piperazin-1-yl)nicotinamide. MS (Q1) 554.0 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101610B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-eb2b610aa65c452497238959e8805b6d |
| Source note | uspto-grants-2012_01 |