HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-4-(methylsulfonyl)phenol → HCID 86654271, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-4-(methylsulfonyl)phenol | HCID 167048 | — |
| Reactant | Tert-Butyl 4-[2-(2-chloro-4-methanesulfonylphenoxymethyl)-3-methylpyridin-5-yl]piperidine-1-carboxylate | HCID 86654270 | — |
| Product | HCID 86654271 | HCID 86654271 | 35% |
Reaction Steps
The title compound was prepared from tert-butyl 4-[(2-hydroxymethyl)pyridin-5-yl]piperidine-1-carboxylate (Example 1(2)) (64 mg, 0.219 mmol) and 4-methanesulfonyl-3-methylphenol (41 mg, 0.219 mmol) following a procedure analogous to that in Example 1(3) and (4) as a pale yellow amorphous (35 mg, yield 35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536176B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-43bf9bde8e1e49f6ab43a469460f182f |
| Source note | uspto-grants-2013_09 |