HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[2-Nitro-3-(3-nitro-phenylamino)-phenyl]-malonic acid dimethyl ester → [2-Nitro-3-(3-nitro-phenylamino)-phenyl]-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[2-Nitro-3-(3-nitro-phenylamino)-phenyl]-malonic acid dimethyl ester | HCID 86623175 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | [2-Nitro-3-(3-nitro-phenylamino)-phenyl]-acetic acid | HCID 59804360 | — |
Reaction Steps
2-[2-Nitro-3-(3-nitro-phenylamino)-phenyl]-malonic acid dimethyl ester (1.26 g, 3.24 mmol) is heated in 6 N hydrochloric acid (100 ml) at 110° C. for 10 hours. It is then cooled to room temperature; the precipitate therefore formed is collected by vacuum filtration to give the desired compound: LC-MS: 318.0 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101608B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-11aaf3d44d0c4f219057899e34b9660f |
| Source note | uspto-grants-2012_01 |