HRID422546

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID59726019

未命名化合物

结构：CCn1nccc1NC(=O)c1ccc(C)c(B2OC(C)(C)C(C)(C)O2)c1

HCID59726035

未命名化合物

PRODUCTS

生成物

结构：CCn1nccc1NC(=O)c1ccc(C)c(-c2ccc3c(NC(C)C)nncc3c2)c1

HCID59726024

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

结构：c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

催化剂HCID178418397

未命名化合物

PROCEDURE

实验过程

This compound was prepared according to the procedure described in Example 2c using the following starting materials: 6-Bromo-N-isopropylphthalazin-1-amine, tetrakis(triphenylphosphine)palladium and N-(1-ethyl-1H-pyrazol-5-yl)-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide. MS (ESI, pos. ion) m/z: 415.2 (M+1).

WORKUP

后处理

customThis compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e5b549fcd4ee495bacf87af6b897703a
来源数据集: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08101612B2
来源说明: uspto-grants-2012_01

反应 SMILES

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([NH:12][CH:13]([CH3:15])[CH3:14])=[N:7][N:6]=[CH:5]2.[CH2:16]([N:18]1[C:22]([NH:23][C:24](=[O:41])[C:25]2[CH:30]=[CH:29][C:28]([CH3:31])=[C:27](B3OC(C)(C)C(C)(C)O3)[CH:26]=2)=[CH:21][CH:20]=[N:19]1)[CH3:17]>C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[CH2:16]([N:18]1[C:22]([NH:23][C:24](=[O:41])[C:25]2[CH:30]=[CH:29][C:28]([CH3:31])=[C:27]([C:2]3[CH:3]=[C:4]4[C:9](=[CH:10][CH:11]=3)[C:8]([NH:12][CH:13]([CH3:15])[CH3:14])=[N:7][N:6]=[CH:5]4)[CH:26]=2)=[CH:21][CH:20]=[N:19]1)[CH3:17]