HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-bromo-N-isopropylphthalazin-1-amine → N-(1-Ethyl-1H-pyrazol-5-yl)-3-(1-(isopropylamino)phthalazin-6-yl)-4-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-bromo-N-isopropylphthalazin-1-amine | HCID 59726019 | — |
| Reactant | N-(1-ethyl-1H-pyrazol-5-yl)-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 59726035 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | N-(1-Ethyl-1H-pyrazol-5-yl)-3-(1-(isopropylamino)phthalazin-6-yl)-4-methylbenzamide | HCID 59726024 | — |
Reaction Steps
This compound was prepared according to the procedure described in Example 2c using the following starting materials: 6-Bromo-N-isopropylphthalazin-1-amine, tetrakis(triphenylphosphine)palladium and N-(1-ethyl-1H-pyrazol-5-yl)-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide. MS (ESI, pos. ion) m/z: 415.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101612B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-e5b549fcd4ee495bacf87af6b897703a |
| Source note | uspto-grants-2012_01 |