1,1,1-Trifluoro-2-propanol → HCID 25129833, compound

HRID 422552Notes

Reaction equation

HRID 422552 reaction equation
[F:1][C:2]([F:7])([F:6])[CH:3]([OH:5])[CH3:4].[H-].[Na+].[Br:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[C:17](Cl)=[N:16][N:15]=[CH:14]2>>[Br:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[C:17]([O:5][CH:3]([CH3:4])[C:2]([F:7])([F:6])[F:1])=[N:16][N:15]=[CH:14]2

Participants

4

Reactant 3

HCID 97741,1,1-Trifluoro-2-propanolHCID 24758Sodium hydrideHCID 220304246-Bromo-1-chlorophthalazine

Product 1

HCID 25129833HCID 25129833, compound

Procedure

This compound was prepared according to the procedure described in Example 2b, but starting with 1,1,1-trifluoropropan-2-ol, sodium hydride and 6-bromo-1-chlorophthalazine. MS (ESI, pos. ion) m/z: 321.9 (M+1).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-598bce3eb55a41db9e44a59aef346a39
Source dataset
uspto-grants-2012_01
Patent number
US08101612B2

Reaction notes

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